Examining Bias in Real-World Studies

ACPE UAN #:   0233-0000-16-031-H04-P

Release Date:  Thursday, April 21, 2016

Expiration Date:   Thursday, April 21, 2019

Activity Type:  Knowledge-based  

Contact Hours:   1.25

Activity Fee:  Member:  $15.00             Non-Member:  $30.00

As an accredited provider, AMCP strictly adheres to the ACPE Standards for Commercial Support and other relevant guidelines and standards to ensure the independence of continuing pharmacy education (CPE) activities.  It is AMCP’s intent that all CPE activities be independent, objective, balanced, evidence-based and free of any commercial bias.   

Target Audience: This repurposed session from the AMCP Annual Meeting 2016 is designed to provide insights and solutions for pharmacists who practice in managed care settings, to help them maintain and enhance their knowledge, skills, and abilities.

Activity Overview

Although evidence from randomized clinical trials (RCTs) is the gold-standard used to establish treatment efficacy or internal validity, the use of RCT evidence to establish “external validity” is limited. Real-world research can complement RCT findings, but it may bear a risk of bias with study results being driven by a multitude of factors other than the studied therapies.

This session will provide a non-technical overview of the risks of bias in real-world studies, and how to evaluate the impact of such risks on the quality and interpretation of study results. This session is intended to help managed care decision-makers evaluate the risk of bias in real-world studies based on case studies. 

Learning Objectives:  

  1. Explain which types of studies can and cannot support causality statements.
  2. Describe how to identify the risk of bias in real-world studies.
  3. Discuss strategies to minimize the risk of bias using case studies.

Schedule of Educational Activity

This CPE online activity consists of a pre-recorded audio/slide presentation, a pre-test (to establish prior knowledge, not required to pass), a post-test with a score of 70% or higher, and a specific online activity evaluation. 

Faculty Relevant Financial Relationships Disclosure: AMCP asks everyone who is in a position to control the content of a continuing pharmacy education activity to disclose all relevant financial relationships with commercial interests. If AMCP determines that a conflict of interest exists as a result of a financial relationship you have (or that your spouse/partner has), we will need to take appropriate steps to resolve the conflict of interest.

  • Jenya Antonova, MS, PhD is employed by Genentech, Inc. as Senior Health Economist, Scientific views and guidance presented by Dr. Antonova do not represent an official position of Genentech, Inc.
  • Rahul Dhanda, PhD, MA reports having no financial relationships with any commercial interests during the past 12 months.
  • AMCP staff report no relevant financial relationships pertinent to this activity: Puneet Singh, PharmD and Ruby Singh, PharmD, BCPS.

Method and CPE Requirements:   

Participants should claim continuing pharmacy education (CPE) credit for this online activity, only if they have not claimed credit for the live activity presented at the AMCP Annual Meeting 2016. 

CPE credit will be processed through the AMCP Learn portal and reported directly to CPE Monitor.  Please allow 24-72 hours for processing and posting in your NABP account.

To receive CPE credit for an AMCP Learn online activity you must:

  • View the entire pre-recorded audio/slide presentation.
  • Successfully complete the post-test with a score of 70% or higher (The post-test will provide feedback.)
  • Complete a specific online activity evaluation.

System Technical Requirements/Viewing Requirements: System Requirements Courses and learning activities are delivered via your Web browser and Acrobat PDF. For all activities you should have a basic comfort level using a computer and navigating the web site.  View the minimum technical and system requirements for online educational activities.

Credit Information

Activity Number Credit Amount Accreditation Period
ACPE UAN #0233-0000-16-031-H04-P 1.25 Contact Hours April 21, 2016 - April 21, 2019