Navigating Changes in Clostridioides difficile Prevention and Treatment

ACPE UAN #:   0233-9999-20-003-H01-P

Release Date: July 15, 2020

Expiration Date:  July 15, 2023

Activity Type:    Knowledge-based

Contact Hours: 1.5 

Activity Fee:  Member:  FREE    Non-Member:  FREE

Target Audience

This knowledge-based activity has been designed to meet the educational needs of pharmacists, physicians, and nurses in managed care settings.

Program Description

Clostridioides difficile (C. diff, previously known as Clostridium difficile) infections are a major health care concern. The Centers for Disease Control and Prevention (CDC) estimates that C. diff causes almost half a million illnesses in the U.S. yearly, and approximately 1 in 5 patients with a C. diff infection will experience one or more recurrent infections. There have been noteworthy advances in the development of C. diff infection prevention and treatment, including a growth in the understanding of the role a patient’s gut microbiome plays.

This session will look at the updated C. diff guidelines, the role a patient’s microbiome plays in new and recurrent infections, pipeline medications, and dive into the comparative effectiveness research (CER) data on these treatments.

Learning Objectives

At the completion of this activity, participants should be able to:

  1. Outline the updated Clostridioides difficile (C. diff) guidelines.
  2. Explain emerging evidence on the role of the microbiome in new and recurrent C. diff infections.
  3. Describe the mechanisms of action, safety, and efficacy data on newly approved and pipeline treatments for C. diff management.
  4. Identify which patients are appropriate for newly approved C. diff treatments.
  5. Review the CER data for available C. diff treatments.


Nicholas Ladikos, PharmD, BCPS, BCGP, BCIDP
Director, Professional Affairs
Alexandria, Virginia

Statement of Commercial Support 

This activity is supported by an unrestricted educational grant from Ferring Pharmaceuticals, Inc.

Joint Providership 

This activity is being provided jointly by AMCP and PRIME® Education, LLC.



Continuing Education Credit – Pharmacists

The Academy of Managed Care Pharmacy (AMCP) is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

As an accredited provider, AMCP strictly adheres to the ACPE Standards for Commercial Support and other relevant guidelines and standards to ensure the independence of continuing pharmacy education (CPE) activities.  It is AMCP’s intent that all CPE activities be independent, objective, balanced, evidence-based and free of any commercial bias.

CPE Requirements:

Participants should claim continuing pharmacy education (CPE) credit for this home study activity only if they have not claimed credit for the live webinar activity presented at the live webinar on July 15, 2020.

To receive credit for an online activity you must:

  • Review the full content of the activity.
  • Successfully complete the post-test (required to pass with a score of 70% or higher, it may be taken a maximum of three times).
  • Complete a specific activity evaluation.

Continuing Education Credit – Physicians and Nurses

In support of improving patient care, this activity has been planned and implemented by PRIME® Education (PRIME) and the Academy of Managed Care Pharmacy (AMCP). PRIME® is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Interprofessional Teams

This activity was planned by and for the healthcare team, and learners will receive 1.5 Interprofessional Continuing Education (IPCE) credits for learning and change.

Physician Credit Designation Statement

PRIME® designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity. 

Nurse Credit Designation Statement 

ANCCLogoPRIME® designates this activity for 1.5 contact hours.

To claim ACCME or ANCC credit for the activity please access and enter program code provided during the educational activity. Questions about CME/CNE credit may be directed to

System Technical Requirements/Viewing Requirements: System Requirements Courses and learning activities are delivered via your Web browser and Acrobat PDF. For all activities, you should have a basic comfort level using a computer and navigating websites.  View the minimum technical and system requirements for continuing education online learning activities.

Credit Information

Activity Number Credit Amount Accreditation Period
ACPE UAN #0233-9999-20-003-H01-P 1.5 Contact Hours July 15, 2020 - July 15, 2023